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Hydroxyphthioceranic acid

Web文献「糖脂質成分フチオセラニン酸(Phthioceranic Acid)とヒドロキシフチオセラニン酸(Hydroxyphthioceranic Acid)の収束的な立体選択的合成」の詳細情報です。J-GLOBAL 科学技術総合リンクセンターは研究者、文献、特許などの情報をつなぐことで、異分野の知や意外な発見などを支援する新しいサービス ... WebSatoshi Yuzawa, ...Jay D. Keasling, in Methods in Enzymology, 2024 3.3 Computer-Aided Design. PKS engineering could be greatly aided by computational tools. Huge amounts of information have accumulated since the discovery of modular PKSs, and several PKS-related databases were developed to store and utilize this information for specific …

Polyketide Synthase - an overview ScienceDirect Topics

Web3 okt. 2024 · Synthesis of ent -BE-43547A 1 reveals a potent hypoxia-selective anticancer agent and uncovers the biosynthetic origin of the APD-CLD natural products. Anti-proliferative compounds that display ... Web1 sep. 2014 · The Aggarwal laboratory reported their hydroxyphthioceranic acid total synthesis in 2014, which was based on their in-house developed stereoselective … the stand netflix series https://bearbaygc.com

A highly stereoselective and flexible strategy for the convergent ...

WebThe synthesis presented here is based on iterative catalytic asymmetric conjugate additions of methylmagnesium bromide for the preparation of the phthioceranic and … WebFor example, incorporating sequential lithiation–borylation and Matteson homologation steps (see Section 4.1) followed by Morken's amination protocol (see Section 2.2) afforded 89 in 52% yield , an intermediate in the synthesis of (+)-kalkitoxin (90). 59 Sequential homologations were also utilised in the synthesis of (+)-hydroxyphthioceranic acid (92) … Web10 jul. 2013 · A Convergent and Stereoselective Synthesis of the Glycolipid Components Phthioceranic Acid and Hydroxyphthioceranic Acid †. Dipl.-Chem. … the stand new orleans

Comparative lipidomics of drug sensitive and resistant

Category:A Highly Stereoselective and Flexible Strategy for the Convergent ...

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Hydroxyphthioceranic acid

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WebHydroxyphthioceranic acid, an octamethyl-branched acid with a propionate substructure in the chain (Figure 1) is found in cell wall components of Mycobacterium tuberculosis ( … Web14 jul. 2007 · The first total synthesis of phthioceranic acid (1) has been achieved by an iterative catalytic asymmetric 1,4-addition protocol. This method provides a robust and …

Hydroxyphthioceranic acid

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Webhexacosanoic acid-C 3 1 H 6 2 O 3: 482.4699: Fatty Acids and Conjugates [FA01] Branched fatty acids [FA0102] LMFA01020321: Hydroxyphthioceranic acid (C33) … WebGene ID: 103623083, updated on 13-Aug-2024. Summary Other designations. phthioceranic/hydroxyphthioceranic acid synthase, probable polyketide synthase 1, probable ...

Webphthioceranic/hydroxyphthioceranic acid synthase Alternative Name(s) PKS2: Reaction catalysed; 8 (S)-methylmalonyl-CoA + 24 H(+) + hexadecanoyl-[(hydroxy)phthioceranic … Web16 sep. 2024 · However, no major differences were observed in phthioceranic acid and hydroxyphthioceranic acid. To further narrow down our search, we have selected WR 0.25 of MS-LAMP for analysis. Through this WR, we have identified unique 1 and 3 m/z in DS and DR MTB strains, respectively.

WebLM ID: LMFA01020325: Common Name: Hydroxyphthioceranic acid (C39) Systematic Name: 2S,4S,6S,8S,10R,12R,14R-heptamethyl-15-hydroxy-dotriacontanoic acid WebThis mycobacterial polyketide enzyme produces the hepta- and octa-methylated fatty acids known as phthioceranic acids, and presumably their hydroxylated versions. Formation of hepta- and octamethylated products depends on whether the enzyme incorporates seven or eight methylmalonyl-CoA extender units, respectively.

WebRelease of 22-Feb-23 2.-.-.-: Transferases 2.3.-.-: Acyltransferases 2.3.1.-: Transferring groups other than amino-acyl groups All UniProtKB/Swiss-Prot entries ...

WebThis process involves sequential asymmetric diboration of a terminal alkene, forming a 1,2-bis (boronic ester), followed by regio- and stereoselective homologation of the primary … the stand novel charactersWebphthioceranic acid. National Institutes of Health Create Alert Alert. Related topics. Related topics 1 relation. Broader (1) Fatty Acids. Papers overview. Semantic Scholar uses AI to … the stand new town theatre edinburghWebAside from the PDIMs and related molecules, PKS-derived moieties are present in SL-1 (as hydroxyphthioceranic acid), DATs, and triacyl trehaloses (TATs). More intriguingly, they are synthesized by homologous enzyme systems, suggesting common genetic origin, and this has in fact aided in the investigation of their properties. the stand newport coastWebacid at the 2- and 2′-position, as well as with the Mtb-specific multimethyl-branched acyl residues phthioceranic acid, hydroxyphthioceranic acid, mycosanoic acid, … mystery themed snacksWeb28 okt. 2014 · A highly stereocontrolled and flexible access to biologically relevant polydeoxypropionates in optically pure form has been developed. Taking advantage of … mystery theater on youtubeWebNMR Spectra of (+)-Hydroxyphthioceranic Acid 17.....93. S-2 General Information All air- and water-sensitive reactions were carried out in oven-dried glassware under a N 2 … the stand new vegasWebGene ID: 106161238, updated on 10-May-2024. Summary. Other designations. uncharacterized protein LOC106161238 the stand new town theatre